Our Research Digests

Welcome to the 77th edition of the Research Digest. This edition of the digest presents articles exploring the feasibility of N-of-1 observational design for the study of ME/CFS, and attribution theory to investigate the relationship between higher perceived stigma and lower functional status found in ME/CFS.

Welcome to the 76th edition of the Research Digest. This edition features articles describing the potential therapeutic benefit of low dose Naltrexone in ME/CFS and a pilot eLORETA study examining the central autonomic network involvement in PEM in ME/CFS.

Welcome to the 75th edition of the Research Digest. This edition features a study investigating pain pressure thresholds during orthostatic stress testing in patients with ME/CFS and another study evaluating hypothalamic/pituitary autoimmunity dysfunction.

Welcome to the 74th edition of the Research Digest. This edition features a systematic review of studies that investigate various sleep characteristics in ME/CFS and a pilot clinical trial of oral melatonin and zinc supplementation.

Welcome to the 73rd edition of the Research Digest featuring a report investigating the availability of preventative programs and their economic benefits for patients with ME/CFS and a review on the use of lymphoblastoid cell lines in studies looking at ME/CFS and other neurological disorders.

Welcome to the 72nd edition of the Research Digest. This fortnight’s edition features the results of an open-label trial looking at the tolerability and efficacy of Immunoglobulin treatment in ME/CFS patients and a study exploring the impact that ME/CFS has on occupational participation.

Welcome to the 71st edition of the Research Digest. This fortnight’s edition features a study investigating the suitability of sCD26 as a diagnostic marker and another looking at the association between ME/CFS symptomology and heart rate variability in male ME/CFS patients.

Welcome to the 70th edition of the Research Digest featuring a study analysing B cell repertoire and another investigating the relationship between OI and deconditioning in ME/CFS patients.

Welcome to the 69th edition of the Research Digest. This edition features a dataset analysis that aimed to find novel diagnostic biomarkers and a cytokine analysis of ME/CFS patients whom developed ME/CFS after contracting infectious mononucleosis.

Welcome to the 68th edition of the Research Digest featuring a review of the most recent research into the molecular basis of ME/CFS and a pilot study that investigates a potential risk factor for familial ME/CFS.

Welcome to the 67th edition of the Research Digest. This edition features two PEM studies. One that investigates the effect that PEM has on the functional connectivity of various brain regions, and the other looking at markers of arterial stiffness when ME/CFS patients are experiencing PEM.

Welcome to the 66th edition of the Research Digest featuring a study investigating the potential of measuring circulating levels of FGF21 and NT-proBNP as diagnostic biomarkers for ME/CFS.

Welcome to the 65th edition of the Research Digest. This fortnight’s edition features a study examining predicting factors of severe versus non-severe ME/CFS and a proteome study.

Welcome to the 64th edition of the Research Digest featuring a study which aimed to determine if there are risk factors that predispose an infectious mononucleosis patient to develop ME/CFS and another that looked at orthostatic stress and its involvement in PEM.

Welcome to the 63rd edition of the Research Digest. This edition features a study investigating the impact that ME/CFS has on the quality of life of a patients’ close family members, and a study identifying and measuring the epigenetic changes in the DNA of ME/CFS patients.

Welcome to the 62nd edition of the Research Digest featuring a study investigating the predictors of tachypnea in ME/CFS patients and a literature review examining GP knowledge and understanding of ME/CFS.

Welcome to the 61st edition of the Research Digest. This fortnight’s edition features a study investigating microRNA expression differences in ME/CFS patients before and after experiencing PEM, and a study that aimed to develop a sensor-based method to track upright activity as a way to measure ME/CFS disease severity.

Welcome to the 60th edition of the Research Digest featuring a study that aimed to determine whether there are differences in cardiac function in ME/CFS patients and a plasma proteomic analysis study.

Welcome to the 59th edition of the Research Digest. This issue features a review article on the eitology of ME/CFS and a systematic review of neuroimaging studies.

Welcome to the 58th edition of the Research Digest featuring a focus group study that aimed to gain insight into the PEM experiences of ME/CFS patients and a cluster analysis study defining subgroups of patients based on several measures of autonomic dysfunction.

Welcome to the 57th edition of the Research Digest featuring the results of the NHMRC ME/CFS Targeted Call for Research funding and a study that aimed to compare the subjective severity scoring of the SF-36 (based on the physical activity subscale) to two objective measures of activity in order to validate the way in which clinical severity is graded in ME/CFS.

Welcome to the 56th edition of the Research Digest. This issue features a systematic review on neuroimaging studies of ME/CFS and a paper that presents a conceptual framework for understanding the pathophysiology of ME/CFS over time.

Welcome to the 55th edition of the Research Digest. This issue includes an Australian MRI study looking at differences in myelin integrity between the brains of ME/CFS patients and healthy control participants.

Welcome to the 54th edition of the Research Digest. This fortnight’s edition includes summary of a functional MRI study exploring brain responses to autonomic challenges in ME/CFS patients with and without temporomandibular disorder.

Welcome to the 53rd edition of the Research Digest. This fortnight’s edition features a ME/CFS focused edition of the journal WORK: A Journal of Prevention, Assessment and Rehabilitation.

Welcome to the 52nd edition of the Research Digest. This fortnight’s edition features a doppler study of cerebral blood flow when performing a 70-degree head-up tilt test and a perspective paper that discuses ways in which healthcare practitioners can support and provide care to ME/CFS patients.

Welcome to the 51st edition of the Research Digest featuring a study aimed at identifying possible epidemiological and/or clinical factors that could be associated with PEM severity and a UK study into the factors that influence the frequency of GP visits by patients with ME/CFS.

Welcome to the 50th edition of the Research Digest! This edition features a study comparing subjective and objective measures of physical activity in ME/CFS patients and a study that measured and assessed factors that impact on health-related quality-of-life measures in adolescents.

Welcome to the 49th edition of the Research Digest featuring a study investigating the role that Human herpesvirus 6A may play in ME/CFS pathogenesis and an Australian literature review on metabolomic dysregulation in ME/CFS.

Welcome to the 48th edition of the Research Digest featuring a study that investigates differences in immune gene SNP expression in ME/CFS and a systematic review on neurological impairments as measured by neuroimaging techniques.